Abstract
Limited information is available on the association of obesity defined by both body mass index (BMI) and waist circumference (WC) with incident hypertension in rural China. A total of 9,174 participants ≥18 years old from rural areas in middle of China, free of hypertension, diabetes, myocardial infarction and stroke, were selected in this cohort study. Questionnaire interview and anthropometric and laboratory measurements were performed at baseline (2007-2008) and follow-up (2013-2014). During the 6 years of follow-up, hypertension developed in 733/3,620 men and 1,051/5,554 women. After controlling for age, education level, smoking, drinking, physical activity, and family history of hypertension, the relative risk of hypertension was lower for participants with high BMI but normal WC than those with both BMI and WC obesity for men 18-39 and 40-59 years old. Women 18-39 years old with normal BMI but high WC showed a 1.96-fold risk of hypertension, and being female with age 40-59 years and high BMI but normal WC was independently associated with hypertension incidence as compared with both normal BMI and WC. BMI is more associated with hypertension as compared with WC in both genders. High WC tends to add additional risk of hypertension in young women.