Generation of an induced pluripotent stem cell line SDPHi002-A from a patient with lung cancer

从肺癌患者体内生成诱导性多能干细胞系 SDPHi002-A

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作者:Dan Ai, Xiaomeng Yang, Xinyu Li, Ning Liu, Xuexue Xie, Yi Liu, Wei Song

Abstract

Here, an induced pluripotent stem cell (iPSC) line from a patient with lung neuroendocrine carcinoma was generated. The iPSCs were developed using nonintegrating episomal vectors carrying OCT4, SOX2, KLF4, BCL-XL and c-MYC. The established iPSCs (SDPHi002-A) had normal karyotype, excellent differentiation potential in vitro, showing pluripotent stem cell morphology and high expression of pluripotent markers.

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