Abstract
Organ donation and transplantation is one of the most powerful and dramatic practices in modern medicine. It is the pinnacle of centuries of dreams, massive amounts of accrued knowledge and impressive technical developments. One organ donor has the potential of saving more than five lives and impacting the quality of life of many others via tissue donation. The clinical team has a responsibility to the donor families and the recipient patient to do everything possible to provide best practices supported by the best evidence. These standardized best practices should come from the published evidence which is adapted for use in the specific environment, culture, and infrastructure of the institution.