The UCSC Genome Browser Database: 2008 update

UCSC 基因组浏览器数据库:2008 年更新

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作者:D Karolchik, R M Kuhn, R Baertsch, G P Barber, H Clawson, M Diekhans, B Giardine, R A Harte, A S Hinrichs, F Hsu, K M Kober, W Miller, J S Pedersen, A Pohl, B J Raney, B Rhead, K R Rosenbloom, K E Smith, M Stanke, A Thakkapallayil, H Trumbower, T Wang, A S Zweig, D Haussler, W J Kent

Abstract

The University of California, Santa Cruz, Genome Browser Database (GBD) provides integrated sequence and annotation data for a large collection of vertebrate and model organism genomes. Seventeen new assemblies have been added to the database in the past year, for a total coverage of 19 vertebrate and 21 invertebrate species as of September 2007. For each assembly, the GBD contains a collection of annotation data aligned to the genomic sequence. Highlights of this year's additions include a 28-species human-based vertebrate conservation annotation, an enhanced UCSC Genes set, and more human variation, MGC, and ENCODE data. The database is optimized for fast interactive performance with a set of web-based tools that may be used to view, manipulate, filter and download the annotation data. New toolset features include the Genome Graphs tool for displaying genome-wide data sets, session saving and sharing, better custom track management, expanded Genome Browser configuration options and a Genome Browser wiki site. The downloadable GBD data, the companion Genome Browser toolset and links to documentation and related information can be found at: http://genome.ucsc.edu/.

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