Mast Cell Infiltration and Subtype Promote Malignant Transformation of Oral Precancer and Progression of Oral Cancer
肥大细胞浸润及亚型促进口腔癌前病变恶性转化及口腔癌进展
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作者：Xin-Jia Cai, Chao-Ran Peng, Jian-Yun Zhang, Xue-Fen Li, Xu Wang, Ying Han, He-Yu Zhang, Xin Peng, Tie-Jun Li
Significance
In this study, we investigated the role of mast cells (MC) in oral precancer and oral cancer and demonstrated that MCs are involved in oral cancer progression and may serve as a potential diagnostic and prognostic marker. It might improve the immunotherapeutic efficacy through developing targeted therapies against MCs.
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