Prognostic significance of EDN/RB, HJURP, p60/CAF-1 and PDLI4, four new markers in high-grade gliomas

EDN/RB、HJURP、p60/CAF-1 和 PDLI4 四种新标志物对高级别胶质瘤的预后意义

阅读：13

作者：Marie de Tayrac, Stephan Saikali, Marc Aubry, Pascale Bellaud, Rachel Boniface, Véronique Quillien, Jean Mosser

期刊：

PLoS One

影响因子：

2.900

时间：

2013

起止号：

2013 Sep 11;8(9):e73332.

doi：

10.1371/journal.pone.0073332

研究方向：

神经、肿瘤

疾病类型：

胶质瘤

Background

Recent studies have highlighted the heterogeneity of gliomas and demonstrated that molecular and genetic analysis could help in their classification and in the design of treatment protocols. In a previous study we have identified a 4-gene signature highly correlated with survival of glioma patients. The

Conclusions

The expression of the EDN/RB, HJURP, p60/CAF-1 and PDLI4 proteins is disrupted in high grade gliomas and increases in the levels of these proteins are closely linked to tumour aggressiveness and poor outcome.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用；引用内容仅为补充信息，不代表本站立场。

2、若认为本页面引用内容涉及侵权，请及时与本站联系，我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容，需注明“来源：[生知库]”并获得授权；使用引用内容的，需自行联系原作者获得许可。

4、投稿及合作请联系：info@biocloudy.com。