Diagnostic Validation of the RealStar(®) Zika Virus Reverse Transcription Polymerase Chain Reaction Kit for Detection of Zika Virus RNA in Urine and Serum Specimens

RealStar®寨卡病毒逆转录聚合酶链式反应试剂盒检测尿液和血清样本中寨卡病毒RNA的诊断验证

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Abstract

With the Zika virus outbreak in South America starting in 2015 and its potential to cause malformation of the fetus in infected women, the need for diagnostic methods became obvious. Until now, only limited data are available on the diagnostic performance of commercial kits. Here, we present data comparing the RealStar(®) Zika Virus RT-PCR Kit 1.0 for detection of Zika virus from 208 serum and urine samples collected in French Guiana with a reference method. Of these, 114 samples tested positive with the RealStar(®) Kit and 111 with the reference method.

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