Comparable detection of HPV using real-time PCR in paired cervical samples and concentrated first-stream urine collected with Colli-Pee device

使用实时PCR检测配对的宫颈样本和用Colli-Pee装置收集的浓缩初段尿液样本中HPV的检出率相当。

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作者：Nilyanimit,Pornjarim,Chaithongwongwatthana,Surasith,Oranratanaphan,Shina,Poudyal,Nimesh,Excler,Jean-Louis,Lynch,Julia,Vongpunsawad,Sompong,Poovorawan,Yong
期刊：Diagnostic Microbiology and Infectious Disease影响因子：1.800
时间：2024起止号：2024 Mar;108(3):116160
doi：10.1016/j.diagmicrobio.2023.116160

Abstract

We compared high-risk human papillomavirus (HPV) detection on first-stream urine from self-sampled collection device (Colli-Pee) and same-day clinician-collected cervical swab in 240 women. Testing with automated cobas 4800 system showed 96.7 % concordance (198 concordant-negative, 34 concordant-positive, Cohen's kappa=0.87). HPV testing on Colli-Pee urine offers advantages for acceptable non-invasive HPV screening.

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