The Largest American Study Comparing Transient Elastography and the Aminotransferase-to-platelet Ratio Index Score, Two Noninvasive Tests for Liver Fibrosis Staging in HIV/HCV Coinfected Patients

美国最大规模研究比较瞬时弹性成像和转氨酶/血小板比值指数评分,这两种无创检测方法用于 HIV/HCV 合并感染患者的肝纤维化分期

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Abstract

OBJECTIVE: Elastography has become the standard of care of diagnostic approaches for liver disease, particularly when dealing with hepatitis C. There areno studies in the inner-city populations of Newark, New Jersey, that describe the comparison of noninvasive markers, such as FibroScan andaminotransferase-to-platelet ratio index (APRI) scoring. METHODS: Using a chart review method, we used a case-control study method of gathering and analyzing the data, using P < or = 0.05 as a significant variable. RESULTS: The outcome of this study indicates that the FibroScan may be a better marker than the APRI score for the staging of liver disease when a patient has hepatitis B or C with or without HIV/AIDS. CONCLUSIONS: This may be a benchmark study to further enhance our understanging of the utility of the fibroscan.

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