Erythropoietin and Soluble Erythropoietin Receptor: A Role for Maternal Vascular Adaptation to High-Altitude Pregnancy
促红细胞生成素和可溶性促红细胞生成素受体:母体血管适应高海拔妊娠的作用
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作者:Gabriel H Wolfson, Enrique Vargas, Vaughn A Browne, Lorna G Moore, Colleen G Julian
Results
HA augmented the pregnancy-associated rise in Epo relative to SL (P = 0.002), despite similar reductions in hemoglobin (Hb) across pregnancy at each altitude (7% to 9%, P < 0.001 for both). HA PreE cases had circulating Epo levels equivalent to those of controls but greater sEpoR (P < 0.05) and reduced Hb (P = 0.06, trend).
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