Abstract
OBJECTIVE: The NIH Toolbox is intended to be responsive to the needs of investigators evaluating neurologic and behavioral function in diverse settings. Early phases of the project involved gathering information and input from potential end users. METHODS: Information was collected through literature and instrument database reviews, requests for information, consensus meetings, and expert interviews and integrated into the NIH Toolbox development process in an iterative manner. RESULTS: Criteria for instrument inclusion, subdomains to be assessed, and preferences regarding instrument cost and length were obtained. Existing measures suitable for inclusion in the NIH Toolbox and areas requiring new measure development were identified. CONCLUSION: The NIH Toolbox was developed with explicit input from potential end users regarding many of its key features.