FORMIN stable kinetochore-microtubule attachments

FORMIN 稳定的动粒-微管连接

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Abstract

Formins are well-known for promoting actin assembly, but they also play a lesser-studied role in microtubule stabilization. In this issue of Developmental Cell, Cheng et al. (2011) demonstrate that the formin homology protein mDia3 is regulated by Aurora B Kinase and contributes to the generation of kinetochore-microtubule attachments in mitosis.

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