Abstract
This editorial discusses the insightful minireview by Rahmati et al. The minireview delves into the role of the aryl hydrocarbon receptor in the development and progression of esophageal squamous cell carcinoma, highlighting its potential as a promising therapeutic target. The authors concisely summarize the current understanding of how aryl hydrocarbon receptor modulation influences immune responses and the tumor microenvironment, offering fresh perspectives on therapeutic strategies. This editorial aimed to emphasize the significance of these findings and their potential impact on future research and clinical practices for the management of esophageal squamous cell carcinoma.