Comparison of the Vidas C. difficile GDH Automated Enzyme-Linked Fluorescence Immunoassay (ELFA) with Another Commercial Enzyme Immunoassay (EIA) (Quik Chek-60), Two Selective Media, and a PCR Assay for gluD for Detection of Clostridium difficile in Fecal Samples

比较 Vidas C. difficile GDH 自动化酶联荧光免疫测定法 (ELFA) 与另一种商业酶免疫测定法 (EIA) (Quik Chek-60)、两种选择性培养基和 gluD PCR 检测法在粪便样本中检测艰难梭菌的性能

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Abstract

Prevention and management of Clostridium difficile infection (CDI) can be improved by rapid and reliable diagnostics. The Vidas C. difficile glutamate dehydrogenase assay had performance comparable to that of the Quik Chek-60 assay (overall agreement, 95%) and a sensitivity of >93%; thus, it is suitable as the first test in two-stage algorithms for a CDI diagnosis.

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