Computer management of oligonucleotide synthesis on cellulose filters

计算机管理纤维素滤膜上的寡核苷酸合成

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Abstract

A computer program, OLIGO, is described which was designed to manage projects involving the synthesis of large numbers of oligonucleotide fragments using cellulose discs as immobilizing support. The program performs the functions of data entry, verification, analysis and modification; the sorting of filters before each step and project status updating after each reaction step; output of the project status at any point and storage of the finalized project data in a permanent reference file.

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