Abstract
BACKGROUND AND OBJECTIVE: It has been proven that peripherally inserted central catheter-related vein thrombosis is a unignorable complication which causes serious harm and economic burden to patients. We designed a study to analyze factors causing peripherally inserted central catheter (PICC)-related vein thrombosis, and find some nursing interventions to reduce the incidence of PICC-related vein thrombosis, and prolong the service time of peripherally inserted central catheters. METHODS: We designed a retrospective analysis. The study participants were 1,538 lung cancer patients who underwent PICCs placement between January 2010 and September 2013. And tried to determine age, gender, indwelling vein, platelet count, prothrombin time, fibrinogen associated with PICC-related vein thrombosis. RESULTS: Of the 1,538 unique PICC placements, 38 patients developed PICC-related vein thrombosis, the incidence was 2.47%. The gender (OR=2.194, P=0.024), indwelling vein (OR=1.955, P=0.006), fibrinogen (OR=2.055, P=0.028) can significantly affect the occurrence of PICC-related vein thrombosis. CONCLUSIONS: Patients' gender, indwelling vein, fibrinogen can affect the occurrence of PICC-related vein thrombosis. Assessing the patients' condition carefully, implementing individual nursing care can reduce the incidence of PICC-related vein thrombosis, and prolong the service time of PICCs.