The First Evaluation of Proteinase K-Resistant Prion Protein (PrPSc) in Korean Appendix Specimens

首次评估韩国阑尾标本中蛋白酶 K 抗性朊病毒蛋白 (PrPSc)

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作者:Sae-Young Won, Yong-Chan Kim, Yu-Ni Lee, Chan-Gyun Park, Woo-Young Kim, Byung-Hoon Jeong

Conclusion

To the best of our knowledge, this was the first evaluation of PrPSc in Korean appendix specimens.

Methods

In the present study, we investigated CJD-related mutations and polymorphisms of the PRNP gene and carried out an examination on PrPSc in appendix specimens of Korean patients after appendectomy.

Results

In all Korean appendix specimens tested, PrPSc bands were not detected.

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