Identification of two voltage-dependent anion channel-like protein sequences conserved in Kinetoplastida

鉴定出动质体中保守的两种电压依赖性阴离子通道样蛋白序列

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Abstract

The eukaryotic porin superfamily consists of two families, voltage-dependent anion channel (VDAC) and Tom40, which are both located in the mitochondrial outer membrane. In Trypanosoma brucei, only a single member of the VDAC family has been described. We report the detection of two additional eukaryotic porin-like sequences in T. brucei. By bioinformatic means, we classify both as putative VDAC isoforms.

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