One step fabrication of hydrogel microcapsules with hollow core for assembly and cultivation of hepatocyte spheroids

一步制备空心水凝胶微胶囊用于肝细胞球体的组装和培养

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作者:Christian Siltanen, Michalitsa Diakatou, Jeremy Lowen, Amranul Haque, Ali Rahimian, Gulnaz Stybayeva, Alexander Revzin

Significance

Our paper combines an interesting new way for making capsules with cultivation of difficult-to-maintain primary epithelial cells (hepatocytes). The microcapsules described here will enable high density suspension culture of hepatocytes or other cells and may be used as building blocks for engineering tissues.

Statement of significance

Our paper combines an interesting new way for making capsules with cultivation of difficult-to-maintain primary epithelial cells (hepatocytes). The microcapsules described here will enable high density suspension culture of hepatocytes or other cells and may be used as building blocks for engineering tissues.

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