Normal translation of human adenovirus mRNA in cell-free lysates prepared from abortively as well as productively infected monkey cells

在由感染失败和成功感染的猴细胞制备的无细胞裂解液中,人腺病毒mRNA的正常翻译均正常。

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Abstract

A variety of mRNAs, including adenovirus-specified mRNAs isolated from infected human cells, were translated with similar efficiencies in S10 cell-free lysates prepared from productively and abortively infected monkey cells. These results may suggest that reduced synthesis of the late viral proteins in abortively infected monkey cells is not due to a defect in the protein-synthesizing apparatus of the cell.

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