A Systematic Analysis of Metal and Metalloid Concentrations in Eight Zebrafish Recirculating Water Systems

八个斑马鱼循环水系统中金属和类金属浓度的系统分析

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作者:Xavier Langa, Patrick Neuhaus, David Lains, Theodora J Stewart, Nadine Borel, Ana C Certal, Joana F Monteiro, Peter Aleström, Eduardo Diaz, Indre Piragyte, Lars Bräutigam, Rodolfo Vázquez, Ruslan Hlushchuk, Lorenz Gfeller, Adrien Mestrot, Moritz Bigalke, Zoltan M Varga, Nadia Mercader

Abstract

Metals and metalloids are integral to biological processes and play key roles in physiology and metabolism. Nonetheless, overexposure to some metals or lack of others can lead to serious health consequences. In this study, eight zebrafish facilities collaborated to generate a multielement analysis of their centralized recirculating water systems. We report a first set of average concentrations for 46 elements detected in zebrafish facilities. Our results help to establish an initial baseline for trouble-shooting purposes, and in general for safe ranges of metal concentrations in recirculating water systems, supporting reproducible scientific research outcomes with zebrafish.

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