Abstract
Liver resection is a major abdominal surgical procedure with its associated complications. A multidisciplinary team approach with appropriate preoperative planning is of utmost importance. The four cases managed successfully under general anaesthesia in a tertiary government hospital put forth a protocol based management for better outcome. The case series help to find out the perioperative anaesthetic challenges in management of liver resection. A 27-years old female and 40-years old male patients were admitted to a tertiary government hospital with diagnosis of hepatocellular malignancy and a 56-years old male and 52-years old female patients with gall bladder malignancy with liver metastases were admitted in the hospital for definitive cure. All patients were posted for tumour resection under general anaesthesia. This case series highlights the optimum preoperative preparation, optimization and discussion of perioperative concerns and anaesthesia management and importance of total intravenous anaesthesia. Role of protocol-based anaesthetic management and knowledge about surgical techniques for minimization of blood loss may decrease morbidity and mortality in liver resection surgery.