Assessment of quality of life in patients of urethral stricture on clean intermittent catheterization following direct vision internal urethrotomy

直视下尿道内切开术后,清洁间歇导尿治疗尿道狭窄患者的生活质量评估

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Abstract

CONTEXT: Clean intermittent catheterization (CIC) after direct vision internal urethrotomy (DVIU). AIMS: The aim is to assess the quality of life (QOL) in patients with urethral strictures on CIC following DVIU. SETTINGS AND DESIGN: Prospective study. MATERIALS AND METHODS: This prospective study was conducted between August 2013 and July 2015 in the Department of Urology at KGMU, Lucknow. We included patients above the age of 18 years with stricture urethra, who were on CIC following direct visual internal urethrotomy. Patients below the age of 18 years, noncompliance, concomitant neurogenic voiding dysfunction, multiple strictures, pan anterior strictures, and posterior stenosis were excluded from the study. A 16 French Foley catheter was used for CIC following DVIU. Patients were evaluated at follow-up visit at 3, 6, and 12 months. At each follow-up visits, patients were assessed using CIC-QOL questionnaire, maximum urine flow rate and complications related to CIC if any. STATISTICAL ANALYSIS USED: Unpaired t-test was used to compare continuous data, and Fisher's exact test was used to analyze categorical data. RESULTS: Among total 144 male patients evaluated, we included 97 patients, who underwent DVIU. Mean age of the study population was 37.7 ± 14.03 years. Most urethral strictures were idiopathic (64.02%) followed by postinflammatory (24.25%). A significant number of patients reported difficulty in performing CIC, which hampered daily activities. No major procedure related complications were reported. Patients who were compliant to CIC reported no stricture recurrence till 6 months follow-up. CONCLUSIONS: CIC following DVIU remains a reasonable adjunctive option. All the parameters of CIC-QOL questionnaire had improved on continuing CIC. Young men on CIC had greater impairment of QOL when compared to aged patients.

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