Antimicrobial Activity of Origanum vulgare Essential Oil against Staphylococcus aureus and Escherichia coli

牛至精油对金黄色葡萄球菌和大肠杆菌的抗菌活性

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作者:Sonia Tejada-Muñoz, Denny Cortez, Jesús Rascón, Segundo G Chavez, Aline C Caetano, Rosa J Díaz-Manchay, Julio Sandoval-Bances, Sonia Huyhua-Gutierrez, Lizandro Gonzales, Stella M Chenet, Rafael Tapia-Limonchi

Conclusions

OEO had a strong antimicrobial activity with a minimum inhibitory concentration (MIC) of 1.90 mg/mL for S. aureus and 0.49 mg/mL for E. coli after 18 h incubation. The minimum bactericidal concentration (MBC) was 7.9 mg/mL against S. aureus and 0.99 mg/mL against E. coli. Thus, OEO could be used as a natural antimicrobial against S. aureus and E. coli infections.

Methods

The composition of OEO was determined by gas chromatography-mass spectrometry (GC-MS).

Results

Compounds included monoterpenes with known antimicrobial activity, such as 2-menthen-1-ol (36.33%), linalyl acetate (9.26%), terpinene-4-ol (9.01%), 4-thujanol (6.33%), menthen (5.81%), sabinene (5.18%), and carvacrol methyl ether (5.14%). Conclusions: OEO had a strong antimicrobial activity with a minimum inhibitory concentration (MIC) of 1.90 mg/mL for S. aureus and 0.49 mg/mL for E. coli after 18 h incubation. The minimum bactericidal concentration (MBC) was 7.9 mg/mL against S. aureus and 0.99 mg/mL against E. coli. Thus, OEO could be used as a natural antimicrobial against S. aureus and E. coli infections.

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