Radical-Polar Crossover Reactions of Dienylboronate Complexes: Synthesis of Functionalized Allylboronic Esters

二烯基硼酸酯配合物的自由基-极性交叉反应:功能化烯丙基硼酸酯的合成

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Abstract

Radical-polar crossover reactions of dienylboronate complexes are applied to the synthesis of functionalized secondary and tertiary allylboronic esters. The transition-metal-free three-component coupling uses readily accessible dienylboronate esters as substrates in combination with various sp(3)/sp(2) carbon nucleophiles and commercial alkyl iodides as radical precursors. In the visible light-initiated radical chain process, two new C-C bonds are formed, and the E-double bond geometry in the product allylboronic esters is controlled with good to excellent selectivity.

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