The association of community health indicators with outcomes for kidney transplant recipients in the United States

美国社区健康指标与肾移植受者预后之间的关联

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Abstract

OBJECTIVE: To evaluate the association of community health indicators with outcomes for kidney transplant recipients. DESIGN: Retrospective observational cohort study using multivariable Cox proportional hazards models. SETTING: Transplant recipients in the United States from the Scientific Registry of Transplant Recipients merged with health indicators compiled from several national databases and the Centers for Disease Control and Prevention, including the National Center for Health Statistics, the Behavioral Risk Factor Surveillance System, and the National Center for Chronic Disease Prevention and Health Promotion. PATIENTS: A total of 100 164 living and deceased donor adult (aged 18 years) kidney transplant recipients who underwent a transplant between January 1, 2004, and December 31, 2010. MAIN OUTCOME MEASURES: Risk-adjusted time to posttransplant mortality and graft loss. RESULTS: Multiple health indicators from recipients' residence were independently associated with outcomes, including low birth weight, preventable hospitalizations, inactivity rate, and smoking and obesity prevalence. Recipients in the highest-risk counties were more likely to be African American (adjusted odds ratio, 1.59, 95% CI, 1.51-1.68), to be younger (aged 18-39 years; 1.46; 1.32-1.60), to have lower educational attainment (

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