Absorption of slow-release iron and effects of ascorbic acid in normal subjects and after partial gastrectomy

缓释铁的吸收以及抗坏血酸对正常人和部分胃切除术后患者的影响

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Abstract

Radiolabelled tablets of slow-release iron and ferrous sulphate containing 50 mg of elemental iron were given to 28 patients, and iron absorption was studied using a whole body counter.There was no significant difference between the absorption of ferrous sulphate and that of slow-release iron in normal subjects, anaemic patients, anaemic and non-anaemic post-gastrectomy patients, or those with coeliac disease. Ascorbic acid potentiated iron absorption, especially in anaemic post-gastrectomy patients.The indications and hazards of slow release iron preparations are discussed.

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