Abstract
Disappearing bone disease is a rare disorder that causes spontaneous and progressive osteolysis and proliferation of lymphatic tissue and blood vessels. It is debilitating and there is evidence of mortality in reported cases including those affecting mandible. A 38-year-old man was diagnosed with disappearing bone disease of the mandible in 2013. This had progressed from being in the right ramus only, and now extends to the lower right first molar and affects the left coronoid process and ramus. Mandibular involvement has shown to be high-risk. In older patients, misdiagnosis can occur without thorough investigation, and education of clinicians needs to be paramount to provide the appropriate treatment for this rare condition. The disease can be debilitating and as such education and support of patients is essential.