Electrochemical Synthesis of Carbazoles by Dehydrogenative Coupling Reaction

通过脱氢偶联反应电化学合成咔唑

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Abstract

A constant current protocol, employing undivided cells, a remarkably low supporting electrolyte concentration, inexpensive electrode materials, and a straightforward precursor synthesis enabling a novel access to N-protected carbazoles by anodic N,C bond formation using directly generated amidyl radicals is reported. Scalability of the reaction is demonstrated and an easy deblocking of the benzoyl protecting group is presented.

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