Point-of-Care Assessment of DCD Livers During Normothermic Machine Perfusion in a Nonhuman Primate Model

非人类灵长类动物模型中常温机器灌注期间 DCD 肝脏的即时护理评估

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作者:Samuel J Kesseli, Jared N Gloria, Nader Abraham, Samantha E Halpern, Greta N Cywinska, Min Zhang, Dimitrios Moris, Robin Schmitz, Brian I Shaw, Zachary W Fitch, Mingqing Song, Cynthia D Guy, Mathew G Hartwig, Stuart Knechtle, Andrew S Barbas

Conclusion

Objective criteria are needed to define graft viability during NMP. Perfusate lactate clearance does not discriminate between viable and nonviable livers during NMP. Perfusate GGT and FMN may represent POC biomarkers predictive of liver injury during NMP.

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