Abstract
A special issue of the journal Dose-Response entitled "State of the Art CT and Image Quality, Radiation and Contrast Dose" is proposed. Technological improvements on CT scanners have the potentiality to reduce the issues related to ionizing radiation administration, opening new insights toward innovative applications also thanks to the contamination of other research fields like artificial intelligence algorithms and additive manufacturing technologies. In order to approach these new research directions, a multidisciplinary team becomes needed, overcoming the clinical and radiological point of view and enriching the workflow with different contributes. The real weight of these afferents on patient's management remains to be assessed and characterized. The main topics will be related to innovative CT applications able to improve patient management and treatment assessment and reduce patients risks due to radiation exposure and iodinated contrast injection.