Abstract
NorA is a Staphylococcus aureus multidrug transporter that exports structurally distinct compounds including fluoroquinolones. In this study norA-like genes of Staphylococcus epidermidis (norA (SEP)) and Staphylococcus haemolyticus (norA (SHAE)) were identified and sequenced. The nucleotide identity of norA (SEP) and norA (SHAE) with norA was 75.3 and 74.1%, respectively, and the amino acid identity 87.7 and 86%, respectively. Inactivation of norA (SEP) increased the ciprofloxacin susceptibility of E. coli DH5α carrying the pB SK 198 norA (SEP) EZ cat norA (SEP) plasmid.