Hemophagocytic lymphohistiocytosis and pelger-huët anomaly associated with colchicine intoxication

噬血细胞性淋巴组织细胞增生症和佩尔格-胡埃特异常与秋水仙碱中毒有关

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Abstract

Colchicine is frequently used in the treatment of familial Mediterranean fever (FMF). First symptoms of colchicine intoxication are gastrointestinal disturbances, such as abdominal cramps, diarrhea, pancytopenia and so on. Herein, we report a female FMF patient with pancytopenia and hemophagocytic lymphohitiocytosis (HLH), following colchicine intoxication for committing suicide. To our knowledge, this is the first reported case of a patient with HLH associated with colchicine intoxication.

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