Abstract
Precise segmentation of retinal vasculature is crucial for the early detection, diagnosis, and treatment of vision-threatening ailments. However, this task is challenging due to limited contextual information, variations in vessel thicknesses, the complexity of vessel structures, and the potential for confusion with lesions. In this paper, we introduce a novel approach, the MSMA Net model, which overcomes these challenges by replacing traditional convolution blocks and skip connections with an improved multi-scale squeeze and excitation block (MSSE Block) and Bottleneck residual paths (B-Res paths) with spatial attention blocks (SAB). Our experimental findings on publicly available datasets of fundus images, specifically DRIVE, STARE, CHASE_DB1, HRF and DR HAGIS consistently demonstrate that our approach outperforms other segmentation techniques, achieving higher accuracy, sensitivity, Dice score, and area under the receiver operator characteristic (AUC) in the segmentation of blood vessels with different thicknesses, even in situations involving diverse contextual information, the presence of coexisting lesions, and intricate vessel morphologies.