Abstract
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: The objective of this review is to determine the effect of surfactant administration on morbidity, mortality and the need for ECMO and assisted ventilation in newborn infants with congenital diaphragmatic hernia. Subgroup analyses will be conducted to separately evaluate different surfactant preparations and prophylactic and rescue strategies of surfactant administration and to compare these two strategies.