Abstract
Prolonged duration of action of rocuronium is rare but has been more frequently reported in infants. Yet it has not been reported in pre-term infants. We present a case of unusually prolonged neuromuscular blockade following a bolus dose of rocuronium administered during rapid sequence induction in a preterm infant leading to difficult weaning from mechanical ventilation. This case highlights the importance of neuromuscular blockade monitoring even after a bolus dose of neuromuscular blockade in (pre-term) neonates.