Targeting uridine diphosphate glucuronosyltransferase 1A1 in liver disease: Current research and future directions

靶向尿苷二磷酸葡萄糖醛酸转移酶1A1治疗肝病:当前研究及未来方向

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Abstract

The current letter to the editor pertains to the manuscript entitled 'Uridine diphosphate glucuronosyltransferase 1A1 prevents the progression of liver injury'. Increased levels of uridine diphosphate glucuronosyltransferase 1A1 during liver injury could mitigate damage by reducing endoplasmic reticulum stress, oxidative stress, and dysregulated lipid metabolism, impeding hepatocyte apoptosis and necroptosis.

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