A Hierarchical Core-Shell Structure of NiO@Cu(2)O-CF for Effective Non-Enzymatic Electrochemical Glucose Detection

用于高效非酶电化学葡萄糖检测的NiO@Cu(2)O-CF分级核壳结构

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Abstract

Non-enzymatic glucose detection is an effective strategy to control the blood glucose level of diabetic patients. A novel hierarchical core-shell structure of nickel hydroxide shell coated copper hydroxide core based on copper foam (Ni(OH)(2)@Cu(OH)(2)-CF) was fabricated and derived from NiO@Cu(2)O-CF for glucose sensing. Cyclic voltammetry and amperometry experiments have demonstrated the efficient electrochemical catalysis of glucose under alkaline conditions. The measurement displays that the fabricated sensor exhibits a detection scale of 0.005-4.5 mM with a detection sensitivity of 4.67 µA/µM/cm(2). It has remarkable response/recovery times in respect of 750 μM glucose (1.0 s/3.5 s). Moreover, the NiO@Cu(2)O-CF shows significant selectivity, reliable reproducibility and long-term stability for glucose determination, suggesting it is a suitable candidate for further applications.

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