Allysine-Targeted Molecular MRI Enables Early Prediction of Chemotherapy Response in Pancreatic Cancer

靶向赖氨酸的分子磁共振成像能够早期预测胰腺癌的化疗反应

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作者:Hua Ma #, Shadi A Esfahani #, Shriya Krishna, Bahar Ataeinia, Iris Y Zhou, Nicholas J Rotile, Jonah Weigand-Whittier, Avery T Boice, Andrew S Liss, Kenneth K Tanabe, Peter Caravan

Significance

Allysine-targeted molecular MRI can quantify fibrogenesis in pancreatic tumors and predict response to chemotherapy, which could guide rapid clinical management decisions by differentiating responders from nonresponders after treatment initiation.

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