ENabling Reduction of Low-grade Inflammation in SEniors Pilot Study: Concept, Rationale, and Design

减少老年人低度炎症的试点研究:概念、原理和设计

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作者:Todd M Manini, Stephen D Anton, Daniel P Beavers, Jane A Cauley, Mark A Espeland, Roger A Fielding, Stephen B Kritchevsky, Christiaan Leeuwenburgh, Kristina H Lewis, Christine Liu, Mary M McDermott, Michael E Miller, Russell P Tracy, Jeremy D Walston, Barbara Radziszewska, Jane Lu, Cindy Stowe, Samu

Conclusion

The ENRGISE Pilot Study will inform a larger subsequent trial that is expected to have important clinical and public health implications for the growing population of older adults with low-grade chronic inflammation and mobility limitations.

Results

Results from the ENRGISE Pilot Study will provide recruitment yields, feasibility, medication tolerance and adherence, and preliminary data to help justify a sample size for a more definitive randomized trial.

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