UniPep--a database for human N-linked glycosites: a resource for biomarker discovery

UniPep——人类 N 连接糖基化位点数据库:生物标志物发现的资源

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作者:Hui Zhang, Paul Loriaux, Jimmy Eng, David Campbell, Andrew Keller, Pat Moss, Richard Bonneau, Ning Zhang, Yong Zhou, Bernd Wollscheid, Kelly Cooke, Eugene C Yi, Hookeun Lee, Elaine R Peskind, Jing Zhang, Richard D Smith, Ruedi Aebersold

Abstract

There has been considerable recent interest in proteomic analyses of plasma for the purpose of discovering biomarkers. Profiling N-linked glycopeptides is a particularly promising method because the population of N-linked glycosites represents the proteomes of plasma, the cell surface, and secreted proteins at very low redundancy and provides a compelling link between the tissue and plasma proteomes. Here, we describe UniPep http://www.unipep.org--a database of human N-linked glycosites--as a resource for biomarker discovery.

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