This work proposes the characterization of the temperature dependence of the thermal properties of heart and lung tissues from room temperature up toâ>â90 °C. The thermal diffusivity (α), thermal conductivity (k), and volumetric heat capacity (C(v)) of ex vivo porcine hearts and deflated lungs were measured with a dual-needle sensor technique. α and k associated with heart tissue remained almost constant untilâ~â70 andâ~â80 °C, accordingly. Aboveâ~â80 °C, a more substantial variation in these thermal properties was registered: at 94 °C, α and k respectively experienced a 2.3- and 1.5- fold increase compared to their nominal values, showing average values of 0.346 mm(2)/s and 0.828 W/(m·K), accordingly. Conversely, C(v) was almost constant until 55 °C and decreased afterward (e.g., C(v)â=â2.42 MJ/(m(3)·K) at 94 °C). Concerning the lung tissue, both its α and k were characterized by an exponential increase with temperature, showing a marked increment at supraphysiological and ablative temperatures (at 91 °C, α and k were equal to 2.120 mm(2)/s and 2.721 W/(m·K), respectively, i.e., 13.7- and 13.1-fold higher compared to their baseline values). Regression analysis was performed to attain the best-fit curves interpolating the measured data, thus providing models of the temperature dependence of the investigated properties. These models can be useful for increasing the accuracy of simulation-based preplanning frameworks of interventional thermal procedures, and the realization of tissue-mimicking materials.
Temperature Dependence of Thermal Properties of Ex Vivo Porcine Heart and Lung in Hyperthermia and Ablative Temperature Ranges.
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作者:Bianchi Leonardo, Bontempi Martina, De Simone Sabrina, Franceschet Martina, Saccomandi Paola
期刊: | Annals of Biomedical Engineering | 影响因子: | 5.400 |
时间: | 2023 | 起止号: | 2023 Jun;51(6):1181-1198 |
doi: | 10.1007/s10439-022-03122-9 |
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