Colloidal quantum dots (QDs) are semiconductor crystals a few nanometers in size. Due to their vibrant colors and unique photoluminescence (PL), QDs are widely utilized in displays, where barrier films provide essential shielding. However, one of the primary challenges of QD applications remains achieving sufficient robustness while keeping costs low. Over the past two decades, significant progress has been made in the encapsulation of QDs within silica matrices, aiming to preserve their original PL properties. Research efforts have evolved from bulk forms to thin films. Silica nanoparticles containing multiple embedded QDs have emerged as particularly promising candidates for practical applications. This review highlights recent advancements in silica-based QD encapsulation, incorporating findings from both the authors' investigations and those of other research groups within the field. Silica glass possesses inherent shielding capabilities, but silane coupling agents such as (3-aminopropyl)trimethoxysilane and (3-mercaptopropyl)trimethoxysilane tend to negatively impact this functionality when they are used alone, partly because of the limited formation of a well-developed glass network structure. However, when judiciously controlled, they can serve as mediators between the QD surface and the surrounding pure silica glass matrix, helping to preserve PL properties and control the morphology of silica particles. This review discusses the potential for achieving exceptional shielding properties through sol-gel glass fabrication at low temperatures, utilizing both tetraethoxysilane and other silane coupling agents.