Cancer Communications

First-line serplulimab plus chemotherapy in extensive-stage small-cell lung cancer: Updated results and biomarker analysis from the ASTRUM-005 randomized clinical trial.

Enhancing antitumor immunity through the combination of cholesterolized TLR7 agonist liposomes and radiotherapy: a role for IL-1β and the inflammasome pathway.

通过胆固醇化 TLR7 激动剂脂质体和放射疗法的结合增强抗肿瘤免疫力：IL-1β 和炎症小体通路的作用

Orchestrated desaturation reprogramming from stearoyl-CoA desaturase to fatty acid desaturase 2 in cancer epithelial-mesenchymal transition and metastasis.

在癌症上皮-间质转化和转移过程中，硬脂酰辅酶A去饱和酶向脂肪酸去饱和酶2的协调去饱和重编程

Helicobacter pylori CagA elevates FTO to induce gastric cancer progression via a "hit-and-run" paradigm.

幽门螺杆菌 CagA 通过“打了就跑”的模式上调 FTO 以诱导胃癌进展

Blocking ITGA5 potentiates the efficacy of anti-PD-1 therapy on glioblastoma by remodeling tumor-associated macrophages.

阻断 ITGA5 可重塑肿瘤相关巨噬细胞，从而增强抗 PD-1 疗法对胶质母细胞瘤的疗效

Radiotherapy-resistant prostate cancer cells escape immune checkpoint blockade through the senescence-related ataxia telangiectasia and Rad3-related protein.

放射治疗耐药的前列腺癌细胞通过衰老相关的毛细血管扩张性共济失调和 Rad3 相关蛋白逃避免疫检查点阻断

N(6)-methyladenosine-regulated exosome biogenesis orchestrates an immunosuppressive pre-metastatic niche in gastric cancer peritoneal metastasis.

N(6)-甲基腺苷调节的外泌体生物发生可调控胃癌腹膜转移的免疫抑制性转移前微环境

Immunosuppressive JAG2(+) tumor-associated neutrophils hamper PD-1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells.

免疫抑制性 JAG2(+) 肿瘤相关中性粒细胞通过介导效应调节性 T 细胞的分化来阻碍卵巢癌中的 PD-1 阻断反应

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2-mediated increase of SOAT2 RNA methylation.

肝细胞癌免疫逃逸的新分子机制：NSUN2介导的SOAT2 RNA甲基化增加

Simvastatin overcomes the pPCK1-pLDHA-SPRINGlac axis-mediated ferroptosis and chemo-immunotherapy resistance in AKT-hyperactivated intrahepatic cholangiocarcinoma.

辛伐他汀可克服 AKT 过度激活的肝内胆管癌中 pPCK1-pLDHA-SPRINGlac 轴介导的铁死亡和化疗免疫疗法耐药性