【文献解析】抗GD2抗体-药物偶联物联合EZH2抑制剂他泽司他增强骨肉瘤治疗效果
1. 领域背景与文献文献英文标题:Combination of anti-GD2 antibody-drug conjugate with EZH2 inhibitor tazemetostat enhances therapeutic efficacy in osteosarcoma;发表期刊:Journal of Experimental & Clinical Cancer Research;影响因子:12.658(2023年);研究领域:骨肉瘤靶向治疗。骨肉瘤是儿童及青少年最
【文献解析】非小细胞肺癌中EGFR–MET外显子14跳跃共突变:临床病理特征、结构建模及治疗意义
1. 领域背景与文献文献英文标题:EGFR–MET exon 14 skipping co-mutations in non-small-cell lung cancer: clinicopathological features, structural modeling, and therapeutic implications;发表期刊:BMC Precision Medicine;影响因子:7.7;研究领域:非小细胞肺癌分子诊断与靶向治疗非小细胞肺癌(NSCLC)是肺癌最
【文献解析】体内CAR-T细胞工程:通过全身基因递送变革细胞免疫治疗
1. 领域背景与文献引入文献英文标题:In vivo CAR-T cell engineering: transforming cellular immunotherapy through systemic gene delivery;发表期刊:Journal of Experimental & Clinical Cancer Research;影响因子:未公开;研究领域:肿瘤免疫治疗(细胞免疫治疗分支)嵌合抗原受体T细胞(CAR-T)治疗自2017年首
【文献解析】TUSC7体细胞突变及表达作为非小细胞肺癌生物标志物的研究
1. 领域背景与文献引入文献英文标题:Somatic TUSC7 mutation is associated with altered transcript stability and stress-dependent functional effects in non-small cell lung cancer;发表期刊:Journal of Experimental & Clinical Cancer Research;影响因子:未公开;研究领域:肿瘤学-非小细胞肺癌生物标志物
【文献解析】基于微小RNA的生物标志物在精准肿瘤学中的应用前景:生物样本类型与定量方法对微小RNA水平的影响研究
1. 领域背景与文献文献英文标题:MicroRNA-based biomarkers hold promise for precision oncology, but standardization and pre-analytical variability remain barriers to clinical use. We performed a technical study to assess how the type of biological material (plasma, serum) and quantification (miRNA-seq
【文献解析】TUSC7体细胞突变及表达作为非小细胞肺癌生物标志物的研究
1. 领域背景与文献引入文献英文标题:Somatic TUSC7 mutation is associated with altered transcript stability and stress-dependent functional effects in non-small cell lung cancer;发表期刊:Journal of Experimental & Clinical Cancer Research;影响因子:未公开;研究领域:肿瘤学-非小细胞肺癌生物标志物
【文献解析】基于微小RNA的生物标志物在精准肿瘤学中的应用前景:生物样本类型与定量方法对微小RNA水平的影响研究
1. 领域背景与文献文献英文标题:MicroRNA-based biomarkers hold promise for precision oncology, but standardization and pre-analytical variability remain barriers to clinical use. We performed a technical study to assess how the type of biological material (plasma, serum) and quantification (miRNA-seq
【文献解析】抗GD2抗体-药物偶联物联合EZH2抑制剂他泽司他增强骨肉瘤治疗效果
1. 领域背景与文献文献英文标题:Combination of anti-GD2 antibody-drug conjugate with EZH2 inhibitor tazemetostat enhances therapeutic efficacy in osteosarcoma;发表期刊:Journal of Experimental & Clinical Cancer Research;影响因子:12.658(2023年);研究领域:骨肉瘤靶向治疗。骨肉瘤是儿童及青少年最
【文献解析】非小细胞肺癌中EGFR–MET外显子14跳跃共突变:临床病理特征、结构建模及治疗意义
1. 领域背景与文献文献英文标题:EGFR–MET exon 14 skipping co-mutations in non-small-cell lung cancer: clinicopathological features, structural modeling, and therapeutic implications;发表期刊:BMC Precision Medicine;影响因子:7.7;研究领域:非小细胞肺癌分子诊断与靶向治疗非小细胞肺癌(NSCLC)是肺癌最
【文献解析】体内CAR-T细胞工程:通过全身基因递送变革细胞免疫治疗
1. 领域背景与文献引入文献英文标题:In vivo CAR-T cell engineering: transforming cellular immunotherapy through systemic gene delivery;发表期刊:Journal of Experimental & Clinical Cancer Research;影响因子:未公开;研究领域:肿瘤免疫治疗(细胞免疫治疗分支)嵌合抗原受体T细胞(CAR-T)治疗自2017年首