Cell Reports Methods

A fluorescent STING ligand sensor for high-throughput screening of compounds that can enhance tumor immunotherapy.

Harmonizing TUNEL with multiplexed iterative immunofluorescence enriches spatial contextualization of cell death.

A cost- and time-efficient method for high-throughput cryoprocessing and tissue analysis using multiplexed tissue molds.

Human MAPT knockin mouse models of frontotemporal dementia for the neurodegenerative research community.

Generation of T cell responses against broad KRAS hotspot neoantigens for cell therapy or TCR discovery.

Graft-seq precisely maps RNA modifications via site-specific chemical grafting strategy.

Dynamic stimulation promotes functional tissue-like organization of a 3D human lymphoid microenvironment model in vitro.

Engineering high-efficiency matriptase substrates using E. coli display for applications in prodrug activation.

Rapid and robust generation of cardiomyocyte-specific crispants in zebrafish using the cardiodeleter system.

Analysis of TEM micrographs with deep learning reveals APOE genotype-specific associations between HDL particle diameter and Alzheimer's dementia

利用深度学习分析 TEM 显微照片，揭示高密度脂蛋白颗粒直径与阿尔茨海默病痴呆之间的 APOE 基因型特异性关联