RSC Chemical Biology

Identification of microproteins with transactivation activity by polyalanine motif selection

通过多聚丙氨酸基序选择鉴定具有转录激活活性的微生物蛋白质

The molecular features of non-peptidic nucleophilic substrates and acceptor proteins determine the efficiency of sortagging.

Synthesis of 4-azido sialic acid for testing against Siglec-7 and in metabolic oligosaccharide engineering.

Synergy of triazolyl substituents at C1 and C3 of galactose for high-affinity and selective galectin-4C inhibition.

Exploring substitution effects on the potential dominant conformations of NBF derivatives leading to functional conversion at the mu opioid receptor.

Structure-guided engineering of a polyphosphate kinase 2 class III from an Erysipelotrichaceae bacterium to produce base-modified purine nucleotides.

Investigating the N-terminal linker histone H1 subtypes as substrates for JmjC lysine demethylases.

研究 N 端连接组蛋白 H1 亚型作为 JmjC 赖氨酸去甲基酶的底物

Photothermal imaging of cellular responses to glucose deprivation.

利用光热成像技术研究细胞对葡萄糖缺乏的反应

RPRD1B's direct interaction with phosphorylated RNA polymerase II regulates polyadenylation of cell cycle genes and drives cancer progression.

RPRD1B 与磷酸化 RNA 聚合酶 II 的直接相互作用调节细胞周期基因的多聚腺苷酸化，并驱动癌症进展

Photoaffinity enabled transcriptome-wide identification of splice modulating small molecule-RNA binding events in native cells.

光亲和力技术能够对天然细胞中剪接调节小分子-RNA结合事件进行全转录组范围的鉴定