Acta Pharmaceutica Sinica B

Reversing metabolic reprogramming by CPT1 inhibition with etomoxir promotes cardiomyocyte proliferation and heart regeneration via DUSP1 ADP-ribosylation-mediated p38 MAPK phosphorylation

通过 Etomoxir 抑制 CPT1 逆转代谢重编程，通过 DUSP1 ADP 核糖基化介导的 p38 MAPK 磷酸化促进心肌细胞增殖和心脏再生

Design, synthesis and pharmacological evaluation of 1,2,3,4-tetrahydrobenzofuro[2,3- c]pyridine derivatives as p21-activated kinase 4 inhibitors for treatment of pancreatic cancer

1,2,3,4-四氢苯并呋喃并[2,3-c]吡啶衍生物的设计、合成及作为p21活化激酶4抑制剂治疗胰腺癌的药理评价

Cyclometalated iridium(III) complex based on isoquinoline alkaloid synergistically elicits the ICD response and IDO inhibition via autophagy-dependent ferroptosis

基于异喹啉生物碱的环金属化铱（III）复合物通过自噬依赖性铁死亡协同引发 ICD 反应和 IDO 抑制

Cerebral endothelial 3-mercaptopyruvate sulfurtransferase improves ischemia-induced cognitive impairment via interacting with protein phosphatase 2A

脑内皮细胞 3-巯基丙酮酸硫转移酶通过与蛋白磷酸酶 2A 相互作用改善缺血引起的认知障碍

Free fatty acid receptor-4 regulates T-cell-mediated allogeneic reaction through activating an aryl hydrocarbon receptor pathway

游离脂肪酸受体-4通过激活芳烃受体通路调节T细胞介导的同种异体反应

N 6-Methyladenosine modification of circDcbld2 in Kupffer cells promotes hepatic fibrosis via targeting miR-144-3p/ Et-1 axis

库普弗细胞中 circDcbld2 的 N6-甲基腺苷修饰通过靶向 miR-144-3p/Et-1 轴促进肝纤维化

Gut microbiota-derived tryptophan metabolites regulated by Wuji Wan to attenuate colitis through AhR signaling activation

戊己丸调节肠道菌群衍生的色氨酸代谢物，通过激活 AhR 信号减轻结肠炎

Iron and siRNA co-encapsulated ferritin nanocages induce ferroptosis synergistically for cancer therapy

铁和 siRNA 共包裹的铁蛋白纳米笼协同诱导铁死亡用于癌症治疗

CDK1-mediated phosphorylation of USP37 regulates SND1 stability and promotes oncogenesis in colorectal cancer.

Design, synthesis and biological evaluation of a novel class of indazole-containing compounds with potent anti-influenza activities targeting the PA-PB1 interface.