Contemporary Clinical Trials

Ultra-processed food intake, gut microbiome, and glucose homeostasis in mid-life adults: Background, design, and methods of a controlled feeding trial.

中年成年人超加工食品摄入量、肠道微生物群和葡萄糖稳态：一项控制喂养试验的背景、设计和方法

Growth and adiposity in newborns study (GAINS): The influence of prenatal DHA supplementation protocol.

新生儿生长与脂肪研究（GAINS）：产前DHA补充方案的影响

Design and baseline characteristics of the Cognitive and Aerobic Resilience for the Brain (CARB) study.

认知和有氧运动对大脑的适应性（CARB）研究的设计和基线特征

Sample size considerations for matched-pair cluster randomization design with incomplete observations of continuous outcomes.

The home air in agriculture pediatric intervention (HAPI) trial: Rationale and methods

家庭空气农业儿科干预 (HAPI) 试验：原理和方法

Rationale and design of the granulocyte-macrophage colony stimulating factor in peripheral arterial disease (GPAD-3) study

外周动脉疾病中粒细胞-巨噬细胞集落刺激因子 (GPAD-3) 研究的原理和设计

Rationale and study design for lifestyle intervention in preparation for pregnancy (LIPP): A randomized controlled trial

妊娠准备生活方式干预 (LIPP) 的原理和研究设计：一项随机对照试验

The rationale and design of the personal diet study, a randomized clinical trial evaluating a personalized approach to weight loss in individuals with pre-diabetes and early-stage type 2 diabetes

个人饮食研究的原理和设计，这是一项随机临床试验，旨在评估糖尿病前期和早期 2 型糖尿病患者的个性化减肥方法

The VITamin D and OmegA-3 TriaL-Depression Endpoint Prevention (VITAL-DEP): Rationale and design of a large-scale ancillary study evaluating vitamin D and marine omega-3 fatty acid supplements for prevention of late-life depression

维生素 D 和 OmegA-3 试验-抑郁症终点预防 (VITAL-DEP)：一项大规模辅助研究的原理和设计，评估维生素 D 和海洋 OmegA-3 脂肪酸补充剂对预防晚年抑郁症的作用

Methods to improve the noninvasive diagnosis and assessment of disease severity in children with suspected nonalcoholic fatty liver disease (NAFLD): Study design.

改善疑似非酒精性脂肪肝 (NAFLD) 儿童疾病严重程度的非侵入性诊断和评估的方法：研究设计