Diabetologia

Detection of enterovirus RNA in pancreas and lymphoid tissues of organ donors with type 1 diabetes.

Dysregulated skeletal muscle myosin super-relaxation and energetics in male participants with type 2 diabetes mellitus.

2 型糖尿病男性患者骨骼肌肌球蛋白超松弛和能量代谢失调

High glucose/ChREBP-induced Hif-1α transcriptional activation in CD4(+) T cells reduces the risk of diabetic kidney disease by inhibiting the Th1 response.

高葡萄糖/ChREBP诱导的CD4(+) T细胞中Hif-1α转录激活通过抑制Th1反应降低糖尿病肾病的风险

Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8(+) T cell activity and biomarker during the evolution of type 1 diabetes.

β细胞胞外囊泡PD-L1作为1型糖尿病发展过程中CD8(+)T细胞活性的新型调节因子和生物标志物

Intestinal neutrophil extracellular traps promote gut barrier damage exacerbating endotoxaemia, systemic inflammation and progression of diabetic retinopathy in type 2 diabetes.

肠道中性粒细胞胞外陷阱会促进肠道屏障损伤，加剧 2 型糖尿病患者的内毒素血症、全身炎症和糖尿病视网膜病变进展

TMEM55A-mediated PI5P signalling regulates alpha cell actin depolymerisation and glucagon secretion.

TMEM55A介导的PI5P信号传导调节α细胞肌动蛋白解聚和胰高血糖素分泌

HEXA-FC protein therapy increases skeletal muscle glucose uptake and improves glycaemic control in mice with insulin resistance and in a mouse model of type 2 diabetes.

HEXA-FC 蛋白疗法可增加骨骼肌葡萄糖摄取，改善胰岛素抵抗小鼠和 2 型糖尿病小鼠模型的血糖控制

Increased inflammation as well as decreased endoplasmic reticulum stress and translation differentiate pancreatic islets from donors with pre-symptomatic stage 1 type 1 diabetes and non-diabetic donors.

炎症增加以及内质网应激和翻译减少，使得来自 1 型糖尿病无症状期供体和非糖尿病供体的胰岛有所区别

Regulating islet stress responses through CD47 activation.

通过 CD47 激活调节胰岛应激反应

Pancreatic exocrine damage induces beta cell stress in zebrafish larvae.

胰腺外分泌损伤可导致斑马鱼幼体β细胞应激